Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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661
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Thermo Scientific Chemicals Teriflunomide
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Thermo Scientific Chemicals Teriflunomide
CAS: 163451-81-8 Molecular Formula: C12H9F3N2O2
| CAS | 163451-81-8 |
|---|---|
| Molecular Formula | C12H9F3N2O2 |
662
Tocris Bioscience™ AZ1 USP25/28 inhibitor
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective USP25 and USP28 inhibitor
| Target | USP28 |
|---|---|
| CAS | 2165322-94-9 |
| Purity | 0.98 |
| Chemical Name or Material | 2-[[[5-Bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]ethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H16BrF4NO2 |
663
Tocris Bioscience™ 7rh
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Potent and selective DDR1 inhibitor; orally bioavailable
664
Tocris Bioscience™ Autophinib
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Potent VPS34 inhibitor
665
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Thermo Scientific Chemicals Tofacitinib citrate
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Thermo Scientific Chemicals Tofacitinib citrate
CAS: 540737-29-9 Molecular Formula: C22H28N6O8
| CAS | 540737-29-9 |
|---|---|
| Molecular Formula | C22H28N6O8 |
666
Tocris Bioscience™ SCOTfluor 510 Fmoc-Dapa-OH
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Fmoc protected fluorescent amino acid for use in solid-phase peptide synthesis to prepare PAINT imaging probes
667
| CAS | 99755-59-6 |
|---|---|
| Molecular Formula | C19H25NOS |
668
Tocris Bioscience™ CPS2
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Potent and selective CDK2 Degrader (PROTAC™)
669
Tocris Bioscience™ WQ 1
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Potent and selective σ1 receptor antagonist; active in vivo
| Target | Sigma1 Receptor Antagonists |
|---|---|
| CAS | 1204401-49-9 |
| Purity | 0.98 |
| Chemical Name or Material | 2,3-Dihydro-2-[1-(phenylmethyl)-4-piperidinyl]-4 H-1-benzothiopyran-4-one |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C21H23NOS |
670
Tocris Bioscience™ BL660-NO
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Nitric oxide activity-based sensing NIR bioluminescent probe
671
Tocris Bioscience™ Santacruzamate A
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Highly potent and selective HDAC2 inhibitor
| Target | Class II Histone Deacetylases Inhibitors |
|---|---|
| CAS | 1477949-42-0 |
| Purity | 0.98 |
| Chemical Name or Material | Ethyl N-[4-oxo-4-[(2-phenylethyl)amino]butyl]carbamate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C15H22N2O3 |
672
Tocris Bioscience™ Janelia Fluor™ 525, Haloalkane
Cell-permeable fluorogenic fluorescent dye with a chloroalkane handle. Application: live-cell imaging as a self-labeling tag substrate
673
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Tocris Bioscience™ Nexinhib20
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Tocris Bioscience™ Nexinhib20
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Rab27 inhibitor (IC50 = 330 nM); inhibits neutrophil exocytosis; active in vivo
| CAS | 331949-35-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4,4-Dimethyl-1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-penten-3-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C15H16N4O3 |
| Formula Weight | 300.31 |
674
Tocris Bioscience™ Suramin hexasodium salt
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Non-selective P2 antagonist
675
Tocris Bioscience™ CP 43
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Greener Choice
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Small and Specialty Supplier Partner
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Potent TAOK inhibitor
| CAS | 850467-66-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1′-biphenyl]-4-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H24N2O2 |