Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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661
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675
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661
Tocris Bioscience™ NSC 617145
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Werner syndrome helicase (WRN) inhibitor
| CAS | 203115-63-3 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 20mM in DMSO |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | NSC 617145 |
| Recommended Storage | Store at -20°C |
| Synonym | 1,1'-(2,2-Dimethyl-1,3-propanediyl)bis[3,4-dichloro-1H-pyrrole-2,5-dione |
| Molecular Formula | C13H10Cl4N2O4 |
| Formula Weight | 400.04 |
662
Tocris Bioscience™ Fenobam
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CAS: 57653-26-6 Molecular Formula: C11H11ClN4O2
| CAS | 57653-26-6 |
|---|---|
| Molecular Formula | C11H11ClN4O2 |
663
Tocris Bioscience™ I-BET 151 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Molecular Formula: C23H21N5O3
| Molecular Formula | C23H21N5O3 |
|---|
664
Tocris Bioscience™ Pomalidomide 4'-alkylC5-acid
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Pomalidomide-alkylC5-carboxylic acid
665
Tocris Bioscience™ RHPS 4 methosulfate
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Telomerase inhibitor
| Target | Telomerase Inhibitors |
|---|---|
| CAS | 390362-78-4 |
| Purity | >98% |
| Chemical Name or Material | 3,11-Difluoro-6,8,13-trimethylquino[4,3,2-kl]acridinium methylsulfate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C22H17F2N2.CH3O4S |
| Formula Weight | 458.48 |
666
Tocris Bioscience™ SMBA 1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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High affinity and selective activator of Bax
| Inhibitors | SMBA 1 |
|---|---|
| Product Type | SMBA 1 |
| Molecular Weight (g/mol) | 315.32 |
| Purity | >98% |
667
Tocris Bioscience™ JTE 607 Dihydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cytokine release inhibitor; anti-inflammatory
| CAS | 188791-09-5 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in water and to 100mM in DMSO |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | JTE 607 dihydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Synonym | N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride |
| Molecular Formula | C25H31Cl2N3O5·2HCl |
| Formula Weight | 597.36 |
669
Tocris Bioscience™ GKA 50
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Glucokinase activator
670
Tocris Bioscience™ Olaparib
Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent PARP inhibitor
| Target | Poly(ADP-ribose) Polymerase Inhibitors |
|---|---|
| CAS | 763113-22-0 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2 H)-phthalazinone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C24H23FN4O3 |
671
Tocris Bioscience™ Thalidomide 4'-ether-PEG3-azide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with PEG linker and terminal azide for onward chemistry
672
Tocris Bioscience™ AZ 20
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Potent and selective ATR kinase inhibitor; antitumor
| Inhibitors | AZ 20 |
|---|---|
| Product Type | AZ 20 |
| Molecular Weight (g/mol) | 412.51 |
| Purity | >98% |
673
Canertinib dihydrochloride, Thermo Scientific™
CAS: 289499-45-2 Molecular Formula: C24 H25 Cl F N5 O3 · 2 H Cl
| CAS | 289499-45-2 |
|---|---|
| Molecular Formula | C24 H25 Cl F N5 O3 · 2 H Cl |
674
R&D Systems™ Cy5-Fuc Labeled M1N1f
Can be used as a ligand for lectins and to study glycan protein interaction, substrate for various glycosidases and glycosyltransferases and a scaffold for the synthesis of various glycan epitopes such as sialyl Lewis X structures.
675
Tocris Bioscience™ PSB 069
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CAS: 78510-31-3 Molecular Formula: C20H12ClN2NaO5S
| CAS | 78510-31-3 |
|---|---|
| Molecular Formula | C20H12ClN2NaO5S |